Article
Transforming growth factor beta 1 genotype and p16 as prognostic factors in head and neck squamous cell carcinoma.
Acta oto-laryngologica - 1 Sept 2012
Lundberg Marie, Leivo Ilmo, Saarilahti Kauko, Mäkitie Antti A, Mattila Petri S
Abstract excerpt
CONCLUSION: Transforming growth factor β1 gene (TGFβ1) genotype is a potential p16 independent prognostic factor predicting response to chemoradiotherapy in head and neck squamous cell carcinoma (HNSCC). OBJECTIVES: Expression of p16 and epidermal growth factor receptor (EGFR) has been reported to be associated with survival in HNSCC. We have previously reported that genetic polymorphism of TGFβ1 is linked with...
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