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Article

C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development.

Development (Cambridge, England) - 1 Apr 2009

Vanderzalm Pamela J, Pandey Amita, Hurwitz Michael E, Bloom Laird, Horvitz H Robert, Garriga Gian

Abstract excerpt

Whereas many molecules that promote cell and axonal growth cone migrations have been identified, few are known to inhibit these processes. In genetic screens designed to identify molecules that negatively regulate such migrations, we identified CRML-1, the C. elegans homolog of CARMIL. Although mammalian CARMIL acts to promote the migration of glioblastoma cells, we found that CRML-1 acts as a negative regulator...

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Identifiers

PMID: 19244282
DOI: 10.1242/dev.026666
PMCID: PMC2685937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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