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Article

The slit receptor EVA-1 coactivates a SAX-3/Robo mediated guidance signal in C. elegans.

Science (New York, N.Y.) - 28 Sept 2007

Fujisawa Kazuko, Wrana Jeffrey L, Culotti Joseph G

Abstract excerpt

The SAX-3/roundabout (Robo) receptor has SLT-1/Slit-dependent and -independent functions in guiding cell and axon migrations. We identified enhancer of ventral-axon guidance defects of unc-40 mutants (EVA-1) as a Caenorhabditis elegans transmembrane receptor for SLT-1. EVA-1 has two predicted galactose-binding ectodomains, acts cell-autonomously for SLT-1/Slit-dependent axon migration functions of SAX-3/Robo,...

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PMID: 17901337
DOI: 10.1126/science.1144874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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