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Article

The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.

Development (Cambridge, England) - 1 Aug 2013

Doi Motomichi, Minematsu Hideki, Kubota Yukihiko, Nishiwaki Kiyoji, Miyamoto Masaaki

Abstract excerpt

Cell migration and axon guidance require proper regulation of the actin cytoskeleton in response to extracellular guidance cues. Rho/Rac small GTPases are essential regulators of actin remodeling. Caenorhabditis elegans CED-10 is a Rac1 homolog that is required for various cellular morphological changes and migration events and is under the control of several guidance signaling pathways. There is still...

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Identifiers

PMID: 23900541
DOI: 10.1242/dev.089722
PMCID: PMC4074257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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