Article
ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans.
Developmental biology - 15 Apr 2011
Yee Callista S, Sybingco Stephanie S, Serdetchania Viktoria, Kholkina Ganna, Bueno de Mesquita Matthew, Naqvi Zafaryab, Park Sang-Hyeon, Lam Karmen, Killeen Marie T
Abstract excerpt
During the development of the nervous system, the migration of many cells and axons is guided by extracellular molecules. These molecules bind to receptors at the tips of the growth cones of migrating axons and trigger intracellular signaling to steer the axons along the correct trajectories. We have identified a novel mutant, enu-3 (enhancer of Unc), that enhances the motor neuron axon outgrowth defects observed...
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