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Article

PLR-1, a putative E3 ubiquitin ligase, controls cell polarity and axonal extensions in C. elegans.

Developmental biology - 1 Feb 2015

Bhat Jaffar M, Pan Jie, Hutter Harald

Abstract excerpt

During embryonic development neurons differentiate and extend axons and dendrites that have to reach their appropriate targets. In Caenorhabditis elegans the AVG neuron is the first neuron to extend an axon during the establishment of the ventral nerve cord, the major longitudinal axon tract in the animal. In genetic screens we isolated alleles of plr-1, which caused polarity reversals of the AVG neuron as well...

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Identifiers

PMID: 25448694
DOI: 10.1016/j.ydbio.2014.11.008

Genes

NAV2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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