Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The cell migration molecule UNC-53/NAV2 is linked to the ARP2/3 complex by ABI-1.

Development (Cambridge, England) - 1 Feb 2009

Schmidt Kristopher L, Marcus-Gueret Nancy, Adeleye Adetayo, Webber Jordan, Baillie David, Stringham Eve G

Abstract excerpt

The shape changes that are required to position a cell to migrate or grow out in a particular direction involve a coordinated reorganization of the actin cytoskeleton. Although it is known that the ARP2/3 complex nucleates actin filament assembly, exactly how the information from guidance cues is integrated to elicit ARP2/3-mediated remodeling during outgrowth remains vague. Previous studies have shown that C....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin-Related Protein 2-3 Complex
Share to Actins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Body Patterning

Share to Caenorhabditis elegans Proteins

Share to Cytoskeletal Proteins

Share to Microfilament Proteins

Share to Motor Neurons

Source

Identifiers

PMID: 19168673
DOI: 10.1242/dev.016816

Genes

NAV2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The cell migration molecule UNC-53/NAV2 is linked to the ARP2/3 complex by ABI-1.PMID 19168673Read ↗

unc-53 controls longitudinal migration in C. elegans.Semantic proximity Read ↗

The Arp2/3 complex, UNC-115/abLIM, and UNC-34/Enabled regulate axon guidance and growth cone filopodia formation in Caenorhabditis elegans.Semantic proximity Read ↗

Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.Semantic proximity Read ↗

The atRA-responsive gene neuron navigator 2 functions in neurite outgrowth and axonal elongation.Semantic proximity Read ↗

Pioneer Axon Navigation Is Controlled by AEX-3, a Guanine Nucleotide Exchange Factor for RAB-3 in Caenorhabditis elegans.Semantic proximity Read ↗

RACK-1 acts with Rac GTPase signaling and UNC-115/abLIM in Caenorhabditis elegans axon pathfinding and cell migration.Semantic proximity Read ↗

ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans.Semantic proximity Read ↗

PLR-1, a putative E3 ubiquitin ligase, controls cell polarity and axonal extensions in C. elegans.Semantic proximity Read ↗

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.Semantic proximity Read ↗

Genetic analysis of growth cone migrations in Caenorhabditis elegans.Semantic proximity Read ↗

The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans.Semantic proximity Read ↗

Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.