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Article

Genetic analysis of growth cone migrations in Caenorhabditis elegans.

Journal of neurobiology - 1 Aug 2000

Merz D C, Culotti J G

Abstract excerpt

Model organisms like Caenorhabditis elegans allow the study of growth cone motility and guidance in vivo. We are using circumferential axon guidance in C. elegans to study both the mechanisms of guidance and the interactions between different guidance systems in vivo. A genetic screen has identified suppressors of the specific axon guidance defects caused by ectopic expression of UNC-5, the repulsive receptor for...

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PMID: 10934329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Research trail→

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Genetic analysis of growth cone migrations in Caenorhabditis elegans.PMID 10934329Read ↗

Axon guidance mechanisms in Caenorhabditis elegans.Semantic proximity Read ↗

ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans.Semantic proximity Read ↗

UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans.Semantic proximity Read ↗

Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans.Semantic proximity Read ↗

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally.Semantic proximity Read ↗

The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans.Semantic proximity Read ↗

unc-53 controls longitudinal migration in C. elegans.Semantic proximity Read ↗

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.Semantic proximity Read ↗

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases.Semantic proximity Read ↗

ENU-3 functions in an UNC-6/netrin dependent pathway parallel to UNC-40/DCC/frazzled for outgrowth and guidance of the touch receptor neurons in C. elegans.Semantic proximity Read ↗

A genetic analysis of axon guidance in the C elegans pharynx.Semantic proximity Read ↗

An UNC-40 pathway directs postsynaptic membrane extension in Caenorhabditis elegans.Semantic proximity Read ↗

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