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Article

ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans.

Developmental biology - 15 Jan 2002

Kishore Ranjana S, Sundaram Meera V

Abstract excerpt

Vulval development in the nematode Caenorhabditis elegans can be divided into a fate specification phase controlled in part by let-60 Ras, and a fate execution phase involving stereotypical patterns of cell division and migration controlled in part by lin-17 Frizzled. Since the small GTPase Rac has been implicated as a downstream target of both Ras and Frizzled and influences cytoskeletal dynamics, we...

Topics

Animals
Animals, Genetically Modified
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
Cell Movement
Disorders of Sex Development
Female
GTP-Binding Proteins
Genes, Dominant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Heterogeneity

Genotype

Guanosine Triphosphate

Helminth Proteins

Mutation

Nerve Tissue Proteins

Phenotype

Receptors, Cell Surface

Source

Identifiers

PMID: 11784116
DOI: 10.1006/dbio.2001.0513

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11784116-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans.PMID 11784116Read ↗

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