Article
Cloning the human SUMO1 promoter.
Molecular biology reports - 1 Mar 2010
Nanos-Webb Angela, Deyrieux Adeline, Bian Xue-lin, Rosas-Acosta Germán, Wilson Van G
Abstract excerpt
Regulation of the sumoylation system at the level of gene expression has not yet been explored. To begin to define transcriptional regulatory features, the promoter region for the SUMO1 gene was cloned from human genomic DNA and characterized. Initially, a 532 base pair fragment upstream of and including the predicted SUMO1 transcription start site (TSS) was cloned and shown to possess promoter activity....
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