Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression.

Gene - 22 Aug 2000

Jessen B A, Qin Q, Rice R H

Abstract excerpt

Expression of keratinocyte transglutaminase (TGM1) is critical for maturation of mammalian epidermis and occurs during squamous metaplasia. Examination of the TGM1 5'-flanking region in transient transfections of human epidermal cells revealed an AP1 site approximately 1.5kb upstream from the transcription start site and a CRE site approximately 0.5kb upstream that, combined, accounted for as much as 90% of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding, Competitive
Share to Cyclic AMP Response Element-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyribonuclease I

Share to DNA Footprinting

Share to Keratinocytes

Share to Response Elements

Share to Transcription Factor AP-1

Share to Transglutaminases

Source

Identifiers

PMID: 10974538
DOI: 10.1016/s0378-1119(00)00291-2

Genes

TGM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression.PMID 10974538Read ↗

A distal region of the human TGM1 promoter is required for expression in transgenic mice and cultured keratinocytes.Semantic proximity Read ↗

AP1 Transcription Factors in Epidermal Differentiation and Skin CancerSemantic proximity Read ↗

Cloning the human SUMO1 promoter.Semantic proximity Read ↗

p63 induces key target genes required for epidermal morphogenesisSemantic proximity Read ↗

Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotypeSemantic proximity Read ↗

Ectopic expression of the nude gene induces hyperproliferation and defects in differentiation: implications for the self-renewal of cutaneous epithelia.Semantic proximity Read ↗

The human involucrin gene contains spatially distinct regulatory elements that regulate expression during early versus late epidermal differentiation.Semantic proximity Read ↗

The distal and proximal regulatory regions of the involucrin gene promoter have distinct functions and are required for in vivo involucrin expression.Semantic proximity Read ↗

Functional interplay between p63 and p53 controls RUNX1 function in the transition from proliferation to differentiation in human keratinocytesSemantic proximity Read ↗

Genetically separable determinants of hair keratin gene expression.Semantic proximity Read ↗

Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice.Semantic proximity Read ↗

Biphasic Regulation of AP-1 Subunits during Human Epidermal Wound HealingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.