Article
Novel mutations of CYP3A4 in fine needle aspiration cytology samples of breast cancer patients and its clinical correlations.
Cancer biomarkers : section A of Disease markers - 1 Jan 2009
Suman G, Jamil Kaiser, Suseela K, Vamsy M Ch
Abstract excerpt
Human Cytochrome P450 3A4 is a major P450 enzyme in the liver and gastrointestinal tract. It plays an important role in the metabolism of a wide variety of drugs, some endogenous steroids, and harmful environmental contaminants. To investigate the interindividual variation in CYP3A4 levels we have carried out a study on the genetic polymorphism of 100 breast cancer subjects using fine needle aspiration cytology...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
