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Article

The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.

Cancer - 1 Dec 2010

Justenhoven Christina, Winter Stefan, Hamann Ute, Haas Susanne, Fischer Hans-Peter, Pesch Beate, Brüning Thomas, Ko Yon-Dschun, Brauch Hiltrud

Abstract excerpt

BACKGROUND: CYP3A enzymes, due to their role in the metabolism of steroid hormones, are suggested to affect carcinogenesis of hormone-related cancers. The purpose of the present study was to evaluate the association between polymorphisms located in CYP3A43, breast cancer risk, and tumor characteristics. METHODS: A 3-plex matrix-assisted laser desorption ionization time of flight mass spectrometry assay has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20715157
DOI: 10.1002/cncr.25508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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