Article
CYP1A1 and GSTP1 gene variations in breast cancer: a systematic review and case-control study.
Familial cancer - 1 Apr 2016
Akhtar Sumaira, Mahjabeen Ishrat, Akram Zertashia, Kayani Mahmood Akhtar
Abstract excerpt
In first part of this study, a systematic review was designed to explore the involvement of CYP1A1 and GSTP1 genes in breast cancerogenesis. Based on systematic review, we designed a study to screen CYP1A1 and GSTP1 genes for mutation and their possible association with breast carcinogenesis. A total of 400 individuals were collected and analyzed by PCR-SSCP. After sequence analysis of coding region of CYP1A1 we...
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