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Article

The Effect of CYP2C19*2 (rs4244285) and CYP17 (rs743572) SNPs on Adriamycin and Paclitaxel based Chemotherapy Outcomes in Breast Cancer Patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jun 2024

Gudur Rashmi A, Bhosale Suresh J, Gudur Anand K, Kale Shivani R, More Ashwini L, Datkhile Kailas D

Abstract excerpt

BACKGROUND: Cytochrome P450 (CYP) are phase I metabolizing enzymes involved in detoxification of chemotherapeutic agents. Among the CYP gene family, including CYP1A1, CYP1B1, CYP2C, CYP2D, CYP2E and CYP17, their significance in cancer susceptibility is well established. However, there remains limited understanding regarding the polymorphisms of CYP2C19*2 and CYP17 and their potential correlation with...

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Identifiers

PMID: 38918659
DOI: 10.31557/APJCP.2024.25.6.1977
PMCID: PMC11382849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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