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Article

Representation of CYP3A4, CYP3A5 and UGT1A4 Polymorphisms within Croatian Breast Cancer Patients' Population.

International journal of environmental research and public health - 23 May 2020

Bojanic Kristina, Kuna Lucija, Bilic Curcic Ines, Wagner Jasenka, Smolic Robert, Kralik Kristina, Kizivat Tomislav, Ivanac Gordana, Vcev Aleksandar, Wu George Y, Smolic Martina

Abstract excerpt

Single nucleotide polymorphism (SNP) in genes encoding drug-metabolizing enzymes (DME) could have a critical role in individual responses to anastrozole. Frequency of CYP3A4*1B, CYP3A5*3 and UGT1A4*2 SNPs in 126 Croatian breast cancer (BC) patients and possible association with anastrozole-induced undesirable side effects were analyzed. Eighty-two postmenopausal patients with estrogen receptor (ER)-positive BC...

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Identifiers

PMID: 32456253
DOI: 10.3390/ijerph17103692
PMCID: PMC7277422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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