Article
Influence of (C1236T and C3435T) Polymorphisms of ABCB1 Gene on Chemotherapy Treatment Outcome and Toxicity in Breast Cancer Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 May 2024
Gudur Rashmi A, Bhosale Suresh J, Gudur Anand K, Kale Shivani R, More Ashwini L, Datkhile Kailas D
Abstract excerpt
BACKGROUND: ATP Binding Cassette Transporters (ABCB1) gene plays an important role in transport of different metabolites and anticancer drugs across the cell membrane. There is lack of knowledge on ABCB1 gene polymorphism and its correlation with Adriamycin or paclitaxel based chemotherapy induced toxicity in breast cancer patients. Therefore in this study, we explored the correlation of ABCB1 polymorphisms gene...
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