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Article

Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2009

Abe Koichiro, Klaften Matthias, Narita Akira, Kimura Tetsuaki, Imai Kenji, Kimura Minoru, Rubio-Aliaga Isabel, Wagner Sibylle, Jakob Thilo, Hrabé de Angelis Martin

Abstract excerpt

Many of inflammatory diseases, including inflammatory arthritis, are multifactorial bases. The Ali18 semidominant mutation induced by N-ethyl-N-nitrosourea in the C3HeB/FeJ (C3H) genome causes spontaneous inflammation of peripheral limbs and elevated immunoglobulin E (IgE) levels in mice. Although the Ali18 locus was mapped to a single locus on chromosome 4, the arthritic phenotype of Ali18/+ mice was completely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19238339
DOI: 10.1007/s00335-009-9170-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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