Article
High resolution mapping of Cia3: a common arthritis quantitative trait loci in different species.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2009
Yu Xinhua, Teng Haidong, Marques Andreia, Ashgari Farahnaz, Ibrahim Saleh M
Abstract excerpt
Murine collagen induced arthritis (CIA) is a widely used model of rheumatoid arthritis (RA). Identification of CIA susceptibility genes will aid in the understanding of RA pathogenesis and development of therapeutic targets. This study aims to identify and refine quantitative trait loci (QTL) controlling CIA. Major CIA clinical traits were evaluated in both (DBA/1xFVB/N) F(2) and advanced intercross line (AIL)...
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