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Article

New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2006

Abe Koichiro, Fuchs Helmut, Lisse Thomas, Hans Wolfgang, Hrabé de Angelis Martin

Abstract excerpt

Inflammation is a complex cellular and humoral response against trauma and infection, and its presence leads to destruction of tissue in humans. The mechanisms that initiate inflammatory diseases remain largely unknown because of complex interactions between multiple genetic and environmental factors during pathogenesis. Animal models for human diseases offer dissection of complex pathogenesis by inbred genetic...

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PMID: 16964445
DOI: 10.1007/s00335-006-0014-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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