Article
Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis.
Genes and immunity - 1 Jun 2012
Glant T T, Adarichev V A, Boldizsar F, Besenyei T, Laszlo A, Mikecz K, Rauch T A
Abstract excerpt
Proteoglycan (PG)-induced arthritis (PGIA) is a murine model of rheumatoid arthritis. Arthritis-prone BALB/c mice are 100% susceptible, whereas the major histocompatibility complex-matched DBA/2 strain is completely resistant to PGIA. To reduce the size of the disease-suppressive loci for sequenc...
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