Article
Modified entropy-based procedure detects gene-gene-interactions in unconventional genetic models.
BMC medical genomics - 23 Apr 2020
Malten Jörg, König Inke R
Abstract excerpt
BACKGROUND: Since it is assumed that genetic interactions play an important role in understanding the mechanisms of complex diseases, different statistical approaches have been suggested in recent years for this task. One interesting approach is the entropy-based IGENT method by Kwon et al. that promises an efficient detection of main effects and interaction effects simultaneously. However, a modification is...
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