Article
SBERIA: set-based gene-environment interaction test for rare and common variants in complex diseases.
Genetic epidemiology - 1 Jul 2013
Jiao Shuo, Hsu Li, Bézieau Stéphane, Brenner Hermann, Chan Andrew T, Chang-Claude Jenny, Le Marchand Loic, Lemire Mathieu, Newcomb Polly A, Slattery Martha L, Peters Ulrike
Abstract excerpt
Identification of gene-environment interaction (G × E) is important in understanding the etiology of complex diseases. However, partially due to the lack of power, there have been very few replicated G × E findings compared to the success in marginal association studies. The existing G × E testing methods mainly focus on improving the power for individual markers. In this paper, we took a different strategy and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.