Article
Identification of new quantitative trait loci in mice with collagen-induced arthritis.
Arthritis and rheumatism - 1 Nov 2004
Bauer Kristin, Yu Xinhua, Wernhoff Patrik, Koczan Dirk, Thiesen Hans-Juergen, Ibrahim Saleh M
Abstract excerpt
OBJECTIVE: Collagen-induced arthritis (CIA) in the mouse is one of the most widely used autoimmune experimental models, with many features similar to rheumatoid arthritis. This study sought to identify potential genetic regulatory mechanisms of CIA in major histocompatibility complex-matched (H2-q) F(2) hybrid mice. METHODS: We used 126 polymorphic markers to perform simple sequence-length polymorphism analysis...
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