Article
Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice.
Genes and immunity - 1 May 2005
Johannesson M, Karlsson J, Wernhoff P, Nandakumar K S, Lindqvist A-K, Olsson L, Cook A D, Andersson A, Holmdahl R
Abstract excerpt
Identification of genes controlling complex diseases has proven to be difficult; however, animal models may pave the way to determine how low penetrant genes interact to promote disease development. We have dissected the Cia5/Eae3 susceptibility locus on mouse chromosome 3 previously identified t...
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