Article
Poly (ADP-ribose) polymerase 1 is required for protein localization to Cajal body.
PLoS genetics - 1 Feb 2009
Kotova Elena, Jarnik Michael, Tulin Alexei V
Abstract excerpt
Recently, the nuclear protein known as Poly (ADP-ribose) Polymerase1 (PARP1) was shown to play a key role in regulating transcription of a number of genes and controlling the nuclear sub-organelle nucleolus. PARP1 enzyme is known to catalyze the transfer of ADP-ribose to a variety of nuclear proteins. At present, however, while we do know that the main acceptor for pADPr in vivo is PARP1 protein itself, by PARP1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
