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The <scp>PARP</scp> family: insights into functional aspects of poly ( <scp>ADP</scp> ‐ribose) polymerase‐1 in cell growth and survival

22 Jun 2016

Abstract excerpt

PARP family members can be found spread across all domains and continue to be essential molecules from lower to higher eukaryotes. Poly (ADP-ribose) polymerase 1 (PARP-1), newly termed ADP-ribosyltransferase D-type 1 (ARTD1), is a ubiquitously expressed ADP-ribosyltransferase (ART) enzyme involved in key cellular processes such as DNA repair and cell death. This review assesses current developments in PARP-1...

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PMID: 27329285
DOI: 10.1111/cpr.12268

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