Article
Poly(ADP-Ribose) Polymerases in Plants and Their Human Counterparts: Parallels and Peculiarities
2 Apr 2019
Abstract excerpt
Poly(ADP-ribosyl)ation is a rapid and transient post-translational protein modification that was described first in mammalian cells. Activated by the sensing of DNA strand breaks, poly(ADP-ribose)polymerase1 (PARP1) transfers ADP-ribose units onto itself and other target proteins using NAD+ as a substrate. Subsequently, DNA damage responses and other cellular responses are initiated. In plants, poly(ADP-ribose)...
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