Article
Use of the clonal assay for the measurement of frequencies of HPRT mutants in T-lymphocytes from five control populations.
Mutation research - 1 Oct 1991
Tates A D, van Dam F J, van Mossel H, Schoemaker H, Thijssen J C, Woldring V M, Zwinderman A H, Natarajan A T
Abstract excerpt
The clonal assay was used to measure frequencies of 6-thioguanine-resistant (HPRT) T-lymphocytes in 111 donors from the following 5 control populations: 55 adult healthy volunteers; 20 untreated cancer patients; 8 healthy hospital workers serving as controls for 9 hospital workers sterilizing equipment with ethylene oxide; 15 factory workers serving as controls for 15 workers occupationally exposed to high doses...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Clone Cells
- Drug Resistance
- Ethylene Oxide
- Humans
- Middle Aged
- Mutagenicity Tests
- Mutation