Article
Association study of CREB1 polymorphisms and suicidality in MDD: results from a European multicenter study on treatment resistant depression.
The International journal of neuroscience - 1 May 2015
Carlberg Laura, Schosser Alexandra, Calati Raffaella, Serretti Alessandro, Massat Isabelle, Papageorgiou Konstantinos, Kocabas Neslihan A, Mendlewicz Julien, Zohar Joseph, Montgomery Stuart A, Souery Daniel, Kasper Siegfried
Abstract excerpt
PURPOSE: Mood disorders are present in more than 90% of suicides, and a genetic vulnerability to suicidality is well established. Numerous lines of evidence relate the transcription factor Cyclic adenosine monophosphate Response Element Binding protein (CREB1) to suicide, and to the aetiology of major depressive disorder (MDD). Our aim was to test for association between CREB1 single nucleotide polymorphisms...
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