Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.

Developmental cell - 1 Feb 2009

Dasgupta Biplab, Milbrandt Jeffrey

Abstract excerpt

AMP-activated protein kinase (AMPK) is an evolutionarily conserved metabolic sensor that responds to alterations in cellular energy levels to maintain energy balance. While its role in metabolic homeostasis is well documented, its role in mammalian development is less clear. Here we demonstrate t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Apoptosis
Share to Central Nervous System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myelin Sheath

Share to Neurons

Share to Oligodendroglia

Share to Retinoblastoma Protein

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 19217427
DOI: 10.1016/j.devcel.2009.01.005
PMCID: PMC2662481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19217427-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.PMID 19217427Read ↗

AMP-activated-protein kinase (AMPK) is an essential sensor and metabolic regulator of retinal neurons and their integrated metabolism with RPESemantic proximity Read ↗

AMPKα-like proteins as LKB1 downstream targets in cell physiology and cancer.Semantic proximity Read ↗

Energy Homeostasis and Cancer Prevention: The AMP-Activated Protein KinaseSemantic proximity Read ↗

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.Semantic proximity Read ↗

Fine-tuning AMPK in physiology and disease using point-mutant mouse modelsSemantic proximity Read ↗

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenanceSemantic proximity Read ↗

NUAK Kinases: Brain-Ovary Axis.Semantic proximity Read ↗

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.Semantic proximity Read ↗

Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson’s disease-associated phenotypes in miceSemantic proximity Read ↗

Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species.Semantic proximity Read ↗

AMPK: An Epigenetic Landscape ModulatorSemantic proximity Read ↗

AMP-activated protein kinase is essential for the maintenance of energy levels during synaptic activationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.