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Article

MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Bhowmik Aditi, Das Sambuddha, Bhattacharjee Abhinandan, Choudhury Biswadeep, Naiding Momota, Deka Sujata, Ghosh Sankar Kumar, Choudhury Yashmin

Abstract excerpt

BACKGROUND: Polymorphisms in the MDM2 309 (T>G) and TP53 72 (G>C) genes are reported to increase the susceptibility to head and neck cancer (HNC) in various populations. The risk for HNC is also strongly associated with etiologic habits such as smoking, alcohol consumption and/or chewing of betel quid (BQ). In a case-control study, we investigated the significance of the above polymorphisms alone, and upon...

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Identifiers

PMID: 26320449
DOI: 10.7314/apjcp.2015.16.14.5767

Genes

MDM2

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MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions.PMID 26320449Read ↗

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