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Article

Crystal structure of the eIF4A-PDCD4 complex.

Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2009

Chang Jeong Ho, Cho Yong Hyun, Sohn Sun Young, Choi Jung Min, Kim Ahreum, Kim Young Chang, Jang Sung Key, Cho Yunje

Abstract excerpt

Tumor suppressor programmed cell death protein 4 (PDCD4) inhibits the translation initiation factor eIF4A, an RNA helicase that catalyzes the unwinding of secondary structure at the 5'-untranslated region of mRNAs and controls the initiation of translation. Here, we determined the crystal structu...

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Share to Apoptosis Regulatory Proteins
Share to Crystallography, X-Ray
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19204291
DOI: 10.1073/pnas.0808275106
PMCID: PMC2651268

Genes

PDCD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19204291-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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