Article
Significant association of RUNX3 T/A polymorphism at intron 3 (rs760805) with the risk of gastric atrophy in Helicobacter pylori seropositive Japanese.
Journal of gastroenterology - 1 Jan 2009
Hishida Asahi, Matsuo Keitaro, Goto Yasuyuki, Mitsuda Yoko, Naito Mariko, Wakai Kenji, Tajima Kazuo, Hamajima Nobuyuki
Abstract excerpt
BACKGROUND: This study aimed to examine the associations of a RUNX3 T/A polymorphism at exon 1 (Asn18Ile) (rs6672420) and another RUNX3 intronic T/A polymorphism (rs760805) with the risk of gastric cancer together with the risk of H. pylori seropositivity and gastric atrophy in Japanese people. METHODS: Study subjects were 583 histologically diagnosed gastric cancer patients and age- and sex-frequency-matched...
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