Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions.

Human immunology - 1 Nov 2007

Achyut B R, Ghoshal Uday C, Moorchung Nikhil, Mittal Balraj

Abstract excerpt

A Toll-like receptor-4 (TLR-4) Asp299Gly and Thr399Ileu substitution reduces responsiveness to Helicobacter pylori (H. pylori) lipopolysaccharide. CagA+ strains of H. pylori are known to be associated with gastroduodenal diseases. Therefore we aimed to evaluate association of TLR-4 substitutions and CagA seropositivity with gastritis and precancerous lesions in a northern Indian population. After upper...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Bacterial
Share to Antigens, Bacterial
Share to Gastritis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Precancerous Conditions

Share to Stomach Neoplasms

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 18082569
DOI: 10.1016/j.humimm.2007.10.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions.PMID 18082569Read ↗

Association of Helicobacter pylori infection with Toll-like receptor-4 Thr399Ile polymorphism increased the risk of peptic ulcer development in North of Iran.Semantic proximity Read ↗

Associations of a TLR4 single-nucleotide polymorphism with H. pylori associated gastric diseases in Iranian patients.Semantic proximity Read ↗

Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese.Semantic proximity Read ↗

Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population.Semantic proximity Read ↗

Toll-like receptor 2 and 4 polymorphisms associated with Helicobacter pylori susceptibility and gastric cancerSemantic proximity Read ↗

Positive association between Toll-like receptor 4 gene +896A/G polymorphism and susceptibility to gastric carcinogenesis: a meta-analysis.Semantic proximity Read ↗

TLR2 Arg677Trp but not TLR2 -196 to -174 ins/del and Arg753Gln polymorphism alter the risk of peptic ulcer in north of Iran.Semantic proximity Read ↗

The relationship between TLR4 rs4986790 and rs4986791 gene polymorphisms and Helicobacter pylori infection in children with gastritis.Semantic proximity Read ↗

Association of polymorphism of TLR4 and CD14 genes with gastroduodenal diseases in Japan.Semantic proximity Read ↗

Association of toll-like receptors 2, 4, 9 and 10 genes polymorphisms and Helicobacter pylori-related gastric diseases in Saudi patients.Semantic proximity Read ↗

Polymorphism rs7521584 in miR‑429 is associated with the severity of atrophic gastritis in patients with Helicobacter pylori infection.Semantic proximity Read ↗

Pathophysiology, Risk Factors, and Advances in the Management of Peptic Ulcers: A Comprehensive ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.