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Article

Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1.

Proceedings of the National Academy of Sciences of the United States of America - 31 Jul 2007

Tzeng Tsai-Yu, Lee Chi-Hua, Chan Li-Wei, Shen C-K James

Abstract excerpt

The polytene chromosomes of Drosophila melanogaster consist of condensed heterochromatin regions most of which are in the chromocenter, telomeres, and the fourth chromosome. Whereas suppressor of variegation 3-9 [SU(VAR)3-9], a histone methyltransferase, is mainly responsible for lysine 9 of histone H3 (H3K9) methylation of the chromocenter and consequent binding of the heterochromatin-protein HP1, the enzyme for...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Enzymologic

Share to Histone-Lysine N-Methyltransferase

Share to Histone Methyltransferases

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Source

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Identifiers

PMID: 17652514
DOI: 10.1073/pnas.0705534104
PMCID: PMC1937528

Genes

SETDB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1.PMID 17652514Read ↗

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