Article
dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development.
Genetics - 1 Jan 2012
Hallson Graham, Hollebakken Robert E, Li Taosui, Syrzycka Monika, Kim Inho, Cotsworth Shawn, Fitzpatrick Kathleen A, Sinclair Donald A R, Honda Barry M
Abstract excerpt
In eukaryotes, the post-translational addition of methyl groups to histone H3 lysine 4 (H3K4) plays key roles in maintenance and establishment of appropriate gene expression patterns and chromatin states. We report here that an essential locus within chromosome 3L centric heterochromatin encodes...
Topics
- Amino Acid Sequence
- Animals
- Apoptosis Regulatory Proteins
- Chromosome Mapping
- DNA, Complementary
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation
- Gene Order
- Genes, Lethal
- Genetic Loci
- Histone Methyltransferases
- Histone-Lysine N-Methyltransferase