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Article

dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development.

Genetics - 1 Jan 2012

Hallson Graham, Hollebakken Robert E, Li Taosui, Syrzycka Monika, Kim Inho, Cotsworth Shawn, Fitzpatrick Kathleen A, Sinclair Donald A R, Honda Barry M

Abstract excerpt

In eukaryotes, the post-translational addition of methyl groups to histone H3 lysine 4 (H3K4) plays key roles in maintenance and establishment of appropriate gene expression patterns and chromatin states. We report here that an essential locus within chromosome 3L centric heterochromatin encodes the previously uncharacterized Drosophila melanogaster ortholog (dSet1, CG40351) of the Set1 H3K4 histone...

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Identifiers

PMID: 22048023
DOI: 10.1534/genetics.111.135863
PMCID: PMC3249358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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