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Article

Multiplexed labeling of viable cells for high-throughput analysis of glycine receptor function using flow cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 May 2009

Gilbert Daniel F, Wilson John C, Nink Virginia, Lynch Joseph W, Osborne Geoffrey W

Abstract excerpt

Flow cytometry is an important drug discovery tool because it permits high-content multiparameter analysis of individual cells. A new method dramatically enhanced screening throughput by multiplexing many discrete fixed cell populations; however, this method is not suited to assays requiring functional cellular responses. HEK293 cells were transfected with unique mutant glycine receptors. Mutant receptor...

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PMID: 19184990
DOI: 10.1002/cyto.a.20703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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