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Article

A novel fluorescent sensor for measurement of CFTR function by flow cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Jun 2013

Vijftigschild Lodewijk A W, van der Ent Cornelis K, Beekman Jeffrey M

Abstract excerpt

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic fibrosis. CFTR-dependent iodide transport measured by fluorescent quenching of ectopically expressed halide-sensitive yellow fluorescent protein (YFP) is widely being used to study CFTR function by microscopy or plate readers. Since YFP fluorescence in these systems is dependent on YFP expression levels and iodide...

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Identifiers

PMID: 23463616
DOI: 10.1002/cyto.a.22275

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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