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Article

Functional reconstitution of glycinergic synapses incorporating defined glycine receptor subunit combinations.

Neuropharmacology - 1 Feb 2015

Zhang Yan, Dixon Christine L, Keramidas Angelo, Lynch Joseph W

Abstract excerpt

Glycine receptor (GlyR) chloride channels mediate fast inhibitory neurotransmission in the spinal cord and brainstem. Four GlyR subunits (α1-3, β) have been identified in humans, and their differential anatomical distributions underlie a diversity of synaptic isoforms with unique physiological and pharmacological properties. To improve our understanding of these properties, we induced the formation of recombinant...

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Identifiers

PMID: 25445488
DOI: 10.1016/j.neuropharm.2014.10.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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