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Article

Origin of carcinoma associated fibroblasts.

Cell cycle (Georgetown, Tex.) - 15 Feb 2009

Haviv Izhak, Polyak Kornelia, Qiu Wen, Hu Min, Campbell Ian

Abstract excerpt

Recent evidence on the genomic integrity of non-malignant cells surrounding carcinoma cells has reinvigorated the discussion about the origin of the altered phenotype exhibited by carcinoma associated fibroblasts. Many hypotheses have been proposed for the origin of these altered cells, including standard connective tissue acute phase and stress response, fibroblast senescence, reciprocal interactions with the...

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PMID: 19182519
DOI: 10.4161/cc.8.4.7669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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