Article
Cancer associated fibroblasts in cancer pathogenesis.
Seminars in cell & developmental biology - 1 Feb 2010
Franco Omar E, Shaw Aubie K, Strand Douglas W, Hayward Simon W
Abstract excerpt
In the past century, gradual but sustained advances in our understanding of the molecular mechanisms involved in the growth and invasive properties of cancer cells have led to better management of tumors. However, many tumors still escape regulation and progress to advanced disease. Until recently, there has not been an organized and sustained focus on the "normal" cells in the vicinity of tumors. Interactions...
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