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Article

Genetic alterations and epigenetic alterations of cancer-associated fibroblasts

30 Nov 2016

Abstract excerpt

Cancer-associated fibroblasts (CAFs) are one major type of component identified in the tumor microenvironment. Studies have focused on the genetic and epigenetic status of CAFs, since they are critical in tumor progression and differ phenotypically and functionally from normal fibroblasts. The present review summarizes the recent achievements in understanding the gene profiles of CAFs and pays special attention...

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Identifiers

PMID: 28123515
DOI: 10.3892/ol.2016.5451

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