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Article

Genetically determined interaction between the dopamine transporter and the D2 receptor on prefronto-striatal activity and volume in humans.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jan 2009

Bertolino Alessandro, Fazio Leonardo, Di Giorgio Annabella, Blasi Giuseppe, Romano Raffaella, Taurisano Paolo, Caforio Grazia, Sinibaldi Lorenzo, Ursini Gianluca, Popolizio Teresa, Tirotta Emanuele, Papp Audrey, Dallapiccola Bruno, Borrelli Emiliana, Sadee Wolfgang

Abstract excerpt

Dopamine modulation of neuronal activity during memory tasks identifies a nonlinear inverted-U shaped function. Both the dopamine transporter (DAT) and dopamine D(2) receptors (encoded by DRD(2)) critically regulate dopamine signaling in the striatum and in prefrontal cortex during memory. Moreov...

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Identifiers

PMID: 19176830
DOI: 10.1523/JNEUROSCI.4858-08.2009
PMCID: PMC2686116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19176830-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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