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Article

The impact of common dopamine D2 receptor gene polymorphisms on D2/3 receptor availability: C957T as a key determinant in putamen and ventral striatum.

Translational psychiatry - 11 Apr 2017

Smith C T, Dang L C, Buckholtz J W, Tetreault A M, Cowan R L, Kessler R M, Zald D H

Abstract excerpt

Dopamine function is broadly implicated in multiple neuropsychiatric conditions believed to have a genetic basis. Although a few positron emission tomography (PET) studies have investigated the impact of single-nucleotide polymorphisms (SNPs) in the dopamine D2 receptor gene (DRD2) on D2/3 receptor availability (binding potential, BPND), these studies have often been limited by small sample size. Furthermore, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28398340
DOI: 10.1038/tp.2017.45
PMCID: PMC5416688

Genes

DRD2

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