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Article

Reverse genetic analysis of a putative, influenza virus M2 HXXXW-like motif in the p7 protein of hepatitis C virus.

Journal of viral hepatitis - 1 Mar 2009

Meshkat Z, Audsley M, Beyer C, Gowans E J, Haqshenas G

Abstract excerpt

SUMMARY: The p7 protein of hepatitis C virus (HCV) has been classified into a family of viral proteins, designated viroporins that form ion channels. The M2 protein of influenza virus is the prototype viroporin and encodes a HXXXW motif that constitutes the main functional element of the M2 channels. Alignment of different p7 proteins revealed that a HXXXW sequence (positions 17-21) is also highly conserved among...

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Identifiers

PMID: 19175872
DOI: 10.1111/j.1365-2893.2008.01064.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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