Article
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions.
PLoS pathogens - 1 Jul 2007
Steinmann Eike, Penin Francois, Kallis Stephanie, Patel Arvind H, Bartenschlager Ralf, Pietschmann Thomas
Abstract excerpt
Hepatitis C virus (HCV) infection is associated with chronic liver disease and currently affects about 3% of the world population. Although much has been learned about the function of individual viral proteins, the role of the HCV p7 protein in virus replication is not known. Recent data, however, suggest that it forms ion channels that may be targeted by antiviral compounds. Moreover, this protein was shown to...
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