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Article

Computational Docking Study of p7 Ion Channel from HCV Genotype 3 and Genotype 4 and Its Interaction with Natural Compounds.

PloS one - 1 Jan 2015

Mathew Shilu, Fatima Kaneez, Fatmi M Qaiser, Archunan Govindaraju, Ilyas Muhammad, Begum Nargis, Azhar Esam, Damanhouri Ghazi, Qadri Ishtiaq

Abstract excerpt

BACKGROUND: The current standard care therapy for hepatitis C virus (HCV) infection consists of two regimes, namely interferon-based and interferon-free treatments. The treatment through the combination of ribavirin and pegylated interferon is expensive, only mildly effective, and is associated with severe side effects. In 2011, two direct-acting antiviral (DAA) drugs, boceprevir and telaprevir, were licensed...

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Identifiers

PMID: 26030803
DOI: 10.1371/journal.pone.0126510
PMCID: PMC4451521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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