Article
Increased -1 ribosomal frameshifting efficiency by yeast prion-like phenotype [PSI+].
FEBS letters - 18 Feb 2009
Park Hee Jung, Park So Jung, Oh Doo-Byoung, Lee Sangho, Kim Yang-Gyun
Abstract excerpt
Programmed -1 ribosomal frameshifting (-1RF) is usually regulated by a slippery sequence and an RNA secondary structure but can be affected by the slippery sequence combined with translational perturbation. Dramatic increases of -1RF efficiencies arise from the slippery sequences in [PSI+], an epigenetic modifier of translation termination fidelity. Curing of [PSI+] abolished such increases of -1RF efficiency....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.