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Article

Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 2005

Wilson Marenda A, Meaux Stacie, Parker Roy, van Hoof Ambro

Abstract excerpt

Yeast strains can reversibly interconvert between [PSI+] and [psi-] states. The [PSI+] state is caused by a prion form of the translation termination factor eRF3. The [PSI+] state causes read-through at stop codons and can lead to phenotypic variation, although the molecular mechanisms causing those phenotypic changes remain unknown. We identify an interaction between [PSI+]-induced phenotypic variation and...

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Identifiers

PMID: 16002465
DOI: 10.1073/pnas.0504557102
PMCID: PMC1173365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation.PMID 16002465Read ↗

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